Italian Meatball Sub Sandwich

Italian Meatball Sub Sandwiches
Italian Meatball Sub Sandwiches

We love our meatballs and have many recipes for them. These are Italian style but are minimalist when it comes to ingredients. Using high quality 80-20 ground beef will yield the best results here. Our favorite application for these is this Italian Meatball Sub sandwich with just enough marinara sauce to make it messy and a generous amount of Parmigiano Reggiano on top.

100% Beef Meatballs

What we like the most about these meatballs is that the beef has a chance to shine through. There is just a bit of oregano and parsley but does not have any Parmigiano or Pecorino cheese, which is a bit different than a lot of recipes out there. Although we do like cheese in our meatballs, it’s not always necessary and when we want the protein to shine through, we leave it out.

If you are looking for another great meatball recipe, we included a pork and beef version in our cookbook, Mangiamo! Learn more about it HERE (Magiamo: The cookbook).

A Hint of Spice

Getting your hands on Calabrian chili peppers isn’t very hard and it’s worth it! There is a great flavor when adding it to these meatballs that is just hard to replicate with anything else.


We hope you enjoy this recipe for Italian Meatball Sub Sandwiches! If you give them a try, leave us a comment below or tag us on Instagram @cooking_with_wine!

Italian Meatball Sub Sandwiches with Homemade Marinara
Italian Meatball Sub Sandwiches with Homemade Marinara Sauce

Looking for more recipes like this? Check these out:

Do you love our recipes?

We work hard to provide you with delicious FREE recipes here on Cooking With Wine. If you love and value our content and want to support our efforts, you can contribute whatever amount you are comfortable with below.

Buy me a coffee

We will continue to provide you with recipes no matter what, so there is no obligation to contribute! Any and all contributions are greatly appreciated!

Thank you for being part of our community! You are the reason we do what we do!

Italian Meatball Sub Sandwich

5 from 1 vote
Course: Lunch, DinnerCuisine: Italian-AmericanDifficulty: Easy


Prep time


Cooking time


Total time



Ready to make this recipe? Click HERE to have the ingredients delivered straight to your door!


  • For the Meatballs
  • ¼ cup panko breadcrumbs

  • 1 lb. 1 ground beef

  • 1 tsp 1 kosher salt

  • 1 1 egg

  • 1 tsp 1 chopped fresh oregano

  • 1 tsp 1 chopped fresh parsley

  • 1 tsp 1 crushed red pepper flakes

  • 1 clove 1 minced garlic

  • 1 Tbsp 1 Calabrian chile peppers

  • For the Sandwiches
  • 4 4 hoagie rolls (1 per person)

  • 1 1 recipe Homemade Marinara (alternatively 1 jar of your favorite marinara or spaghetti sauce)

  • 8 slices 8 provolone cheese (optional)

  • Parmigiano Reggiano, freshly grated

  • Fresh basil for garnish


  • Form the meatballs
  • Measure out the panko breadcrumbs, then place them into a food processor for about 5-7 seconds to break them up a little. Add the breadcrumbs and the rest of the ingredients to a large bowl and mix the mixture well by hand.
  • Form the meatballs: if you are measuring by weight, 38 grams each is ideal. Let the meatballs sit for about 15 minutes in the refrigerator. Remove and reshape a little if needed before cooking.
  • Cook the meatballs
  • Preheat the oven to 410°F. These meatballs can be placed on a sheet tray or in a mini muffin tin – either works. Place in the preheated oven for about 20 minutes. While the meatballs cook, gently heat your marinara in a saucepan for serving.
  • After 20 minutes, remove the pan from the oven and then remove the meatballs from the pan and assemble your sandwich.
  • Assemble Your Sandwich
  • To assemble your sandwich, split the hoagie roll and place the cheese slices (optional) on the inside (2 per hoagie). Toast the hoagie roll briefly in a toaster oven or broil in your oven to melt the cheese and toast the bread slightly.
  • Once toasted, add a little of your marinara followed by the meatballs, then more marinara. Top with freshly grated parmesan cheese and basil. Enjoy!

Did you make this recipe?

Tag @cooking_with_wine on Instagram and hashtag it #cookingwithwineblog

Leave a Reply

Your email address will not be published. Required fields are marked *

CookingWithWine©Copyright 2021. All rights reserved.